Date published: 2026-4-24

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Fucosylated monosialoganglioside GM1 (NH4+ salt) (CAS 71812-11-8)

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CAS Number:
71812-11-8
Molecular Weight:
1710.01
Molecular Formula:
C79H141N3O35•NH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fucosylated monosialoganglioside GM1 (NH4+ salt), also known as Fucosyl-GM1, is a fucose-containing glycosphingolipid. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis, and metastasis. Fucosyl-GM1 is a type of ganglioside that is associated with tumors and is an antigen expressed in small cell lung cancer. It is being studied as a target for vaccines against cancer cells. Fucosyl-GM1 has been found to have similar binding properties to GM1 ganglioside, including affinity for cholera toxin B subunit and interaction with amyloid-beta protein.


Fucosylated monosialoganglioside GM1 (NH4+ salt) (CAS 71812-11-8) References

  1. Novel polysialogangliosides of skate brain structural determination of tetra, penta and hexasialogangliosides with a NeuAc-GalNAc linkage.  |  Nakamura, K., et al. 2000. Eur J Biochem. 267: 5198-208. PMID: 10931205
  2. Fucosyl-GM1 expression and amyloid-beta protein accumulation in PC12 cells.  |  Yanagisawa, M., et al. 2006. J Neurosci Res. 84: 1343-9. PMID: 16941490
  3. Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host Cells.  |  Wands, AM., et al. 2018. ACS Infect Dis. 4: 758-770. PMID: 29411974
  4. Fucosyl monosialoganglioside: Quantitative analysis of specific potential biomarkers of lung cancer in biological matrices using immunocapture extraction/tandem mass spectrometry.  |  Ranasinghe, A., et al. 2018. Rapid Commun Mass Spectrom. 32: 1481-1490. PMID: 29876976
  5. Developmental changes of gangliosides of the rat stomach. Appearance of a blood group B-active ganglioside.  |  Bouhours, JF., et al. 1987. J Biol Chem. 262: 16370-5. PMID: 3680254
  6. Fluctuations in levels of various gangliosides in the different tracts of the oviduct of the frog (Rana esculenta) during the reproductive cycle.  |  Giuliani, A., et al. 1995. Ital J Biochem. 44: 75-88. PMID: 7558766

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fucosylated monosialoganglioside GM1 (NH4+ salt), 500 µg

sc-280721
500 µg
$947.00