Anti-DECR1 Antibody G-10 è un monoclonale di topo IgG1 (kappa light chain) DECR1 antibody fornito in 200 µg/ml
generato contro gli amminoacidi 90-335 mappati al C-terminus di DECR1 di origine human
DECR1 Antibody (G-10) é raccomandato per il rilevamento di DECR1 di originehuman e avian in WB, IP, IF, IHC(P) e ELISA; anche reattivo con ulteriori specie, incluse e equine, canine, bovine, porcine and avian
DECR1 Antibody (G-10) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Vedi m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), le nostre alternative ricombinanti ai reagenti secondari convenzionali anti-mouse IgG altamente raccomandate.
Contattaci per ricevere un FREE 10 µg sample di DECR1 (G-10): sc-393473.
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DECR1 Antibody (G-10) is a high quality monoclonal DECR1 antibody (also designated DECR1 antibody) suitable for the detection of the DECR1 protein of human origin. DECR1 Antibody (G-10) is available as both the non-conjugated anti-DECR1 antibody form, as well as multiple conjugated forms of anti-DECR1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Beta oxidation refers to the enzymatic process by which Acyl-CoA is catalytically broken down to yield Acetyl-CoA, the first molecule required for the Krebs cycle. DECR1 (2,4-dienoyl-CoA reductase, mitochondrial), also known as DECR, is a 335 amino acid mitochondrial protein that exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. Expressed in heart, pancreas, liver, lung, kidney and skeletal muscle, DECR1 functions as an auxiliary enzyme of beta-oxidation where it participates in the metabolism of unsaturated fatty enoyl-CoA esters. Specifically, DECR1 uses NADP+ to catalyze the reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA, which can then be used as an intermediate in the Krebs cycle. Additionally, DECR1 is thought to function as a tumor suppressor, possibly down regulating the expression of Neu and slowing the rate of tumorigenesis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Can DECR1 Antibody (G-10): sc-393473, used to detect mouse Decr1?
Richiesta da: AmrGhanam
Thank you for your question. We have not yet tested this antibody in mouse samples, and so that is not a recommended species at this time.
Risposta da: Technical Support
Data di pubblicazione: 2019-04-13
Can DECR1 (G-10): sc-393473 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Richiesta da: Professor Griffin
Thank you for your question. Yes, DECR1 (G-10): sc-393473 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Rated 5 di
Very good Western blot data of DECR1 expressionVery good Western blot data of DECR1 expression in Hep G2, RT-4 and U-251-MG whole cell lysates and human heart and human liver tissue extracts. -SCBT QC
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