Molecular structure of Clomipramine hydrochloride, CAS Number: 17321-77-6
Clomipramine hydrochloride (CAS 17321-77-6)
See product citations (2)
Alternate Names:
Anafranil hydrochloride
Application:
Clomipramine hydrochloride is a selective ST, SLC6A2, and DAT inhibitor
CAS Number:
17321-77-6
Purity:
≥98%
Molecular Weight:
351.32
Molecular Formula:
C19H23ClN2•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Clomipramine hydrochloride is extensively used in research focused on understanding neurotransmitter systems, particularly serotonin and its role in various neural processes. This chemical serves as a tool in models to study the effects of altered serotonin uptake mechanisms. Clomipramine hydrochloride is often utilized in behavioral studies to assess changes in response to altered neurotransmitter levels. Researchers use this compound to explore the underlying mechanisms of obsessive-compulsive behaviors, providing insights that are critical for broader biological and neurological studies. Additionally, Clomipramine hydrochloride is involved in research aimed at understanding the modulation of neural circuits and the impact of neurotransmitter balance on behavior.
Clomipramine hydrochloride (CAS 17321-77-6) References
- Effects of clomipramine hydrochloride on dominance-related aggression in dogs. | White, MM., et al. 1999. J Am Vet Med Assoc. 215: 1288-91. PMID: 10553439
- Effects of clomipramine hydrochloride on heart rate and rhythm in healthy dogs. | Pouchelon, JL., et al. 2000. Am J Vet Res. 61: 960-4. PMID: 10951990
- Effects of monoamine uptake inhibitors on extracellular and platelet 5-hydroxytryptamine in rat blood: different effects of clomipramine and fluoxetine. | Ortiz, J. and Artigas, F. 1992. Br J Pharmacol. 105: 941-6. PMID: 1387022
- The effects of clomipramine hydrochloride in cats with psychogenic alopecia: a prospective study. | Mertens, PA., et al. 2006. J Am Anim Hosp Assoc. 42: 336-43. PMID: 16960036
- Surfactants and ureas affect the cloud point of amphiphilic drug, clomipramine hydrochloride. | Naqvi, AZ., et al. 2010. Colloids Surf B Biointerfaces. 81: 152-7. PMID: 20674295
- Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. | McTavish, D. and Benfield, P. 1990. Drugs. 39: 136-53. PMID: 2178909
- Clomipramine: an antiobsessional tricyclic antidepressant. | Peters, MD., et al. 1990. Clin Pharm. 9: 165-78. PMID: 2180623
- Clomipramine: a tricyclic antidepressant effective in obsessive compulsive disorder. | Kelly, MW. and Myers, CW. 1990. DICP. 24: 739-44. PMID: 2197816
- The demethylation of imipramine and clomipramine as apparent from their plasma kinetics. | Nagy, A. and Johansson, R. 1977. Psychopharmacology (Berl). 54: 125-31. PMID: 412206
- Antagonism of the effects on thermoregulation of delta9-tetrahydrocannabinol by clomipramine in the rat. | Fennessy, MR. and Taylor, DA. 1978. Br J Pharmacol. 63: 267-73. PMID: 667419
- Single-dose kinetics of clomipramine: relationship to the sparteine and S-mephenytoin oxidation polymorphisms. | Nielsen, KK., et al. 1994. Clin Pharmacol Ther. 55: 518-27. PMID: 8181196
- Evaluation of short-term and long-term treatment of the narcolepsy syndrome with clomipramine hydrochloride. | Guilleminault, C., et al. 1976. Acta Neurol Scand. 54: 71-87. PMID: 936975
- Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. | Owens, MJ., et al. 1997. J Pharmacol Exp Ther. 283: 1305-22. PMID: 9400006
Inhibitor of:
AR, ARG-Vasopressin, CYP2D11, DAT, PCP-4, ST, and TRAP.Activator of:
FEV.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Clomipramine hydrochloride, 1 g | sc-203898 | 1 g | $38.00 |