Date published: 2026-7-13

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PRAME Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PRAME Antibodies for research focused on understanding PRAME (Preferentially Expressed Antigen in Melanoma). PRAME Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PRAME functions as a cancer/testis antigen with a significant role in tumor immune evasion and shows associations with various malignancies, including melanoma and leukemia. Expression of PRAME is typically restricted to the testis, making it an attractive target for cancer immunotherapy research. Investigating PRAME can reveal important insights into tumor biology and potential therapeutic approaches. Current research indicates PRAME may serve as a biomarker for disease progression and treatment response in certain cancers. Ongoing studies continue to uncover new functions and regulatory mechanisms of PRAME in cancer development. Understanding PRAME's molecular interactions helps identify novel therapeutic targets and strategies. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of PRAME and its implications in cancer biology.

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PRAME Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PRAME Antibody (D-12)

sc-166480mouse IgG2a κ126-205 (h)WB, IP, IF, ELISAh

new

(1)

PRAME Antibody (H-10)

sc-137188mouse IgG1 κ126-205 (h)WB, IP, IF, ELISAh
5
(3)

PRAME siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PRAME siRNA (h)

sc-37322hGene SilencingN/A0
(0)

PRAME shRNA Plasmid (h)

sc-37322-SHhGene SilencingPuromycin0
(0)

PRAME shRNA (h) Lentiviral Particles

sc-37322-VhGene SilencingPuromycin0
(0)

PRAME like-1 siRNA (m)

sc-37323mGene SilencingN/A0
(0)

PRAME like-1 shRNA Plasmid (m)

sc-37323-SHmGene SilencingPuromycin0
(0)

PRAME like-1 shRNA (m) Lentiviral Particles

sc-37323-VmGene SilencingPuromycin0
(0)

PRAMEF1 siRNA (h)

sc-76215hGene SilencingN/A0
(0)

PRAMEF1 shRNA Plasmid (h)

sc-76215-SHhGene SilencingPuromycin0
(0)

PRAMEF1 shRNA (h) Lentiviral Particles

sc-76215-VhGene SilencingPuromycin0
(0)

PRAMEF2 siRNA (h)

sc-76223hGene SilencingN/A0
(0)

PRAMEF2 shRNA Plasmid (h)

sc-76223-SHhGene SilencingPuromycin0
(0)

PRAMEF2 shRNA (h) Lentiviral Particles

sc-76223-VhGene SilencingPuromycin0
(0)

PRAMEF3 siRNA (h)

sc-76225hGene SilencingN/A0
(0)

PRAMEF3 shRNA Plasmid (h)

sc-76225-SHhGene SilencingPuromycin0
(0)

PRAMEF3 shRNA (h) Lentiviral Particles

sc-76225-VhGene SilencingPuromycin0
(0)

PRAMEF4 siRNA (h)

sc-76227hGene SilencingN/A0
(0)

PRAMEF4 shRNA Plasmid (h)

sc-76227-SHhGene SilencingPuromycin0
(0)

PRAMEF4 shRNA (h) Lentiviral Particles

sc-76227-VhGene SilencingPuromycin0
(0)

PRAME like-5 siRNA (m)

sc-76214mGene SilencingN/A0
(0)

PRAME like-5 shRNA Plasmid (m)

sc-76214-SHmGene SilencingPuromycin0
(0)

PRAME like-5 shRNA (m) Lentiviral Particles

sc-76214-VmGene SilencingPuromycin0
(0)

PRAMEF5 siRNA (h)

sc-76229hGene SilencingN/A0
(0)

PRAMEF5 shRNA Plasmid (h)

sc-76229-SHhGene SilencingPuromycin0
(0)

PRAMEF5 shRNA (h) Lentiviral Particles

sc-76229-VhGene SilencingPuromycin0
(0)

PRAME like-6 siRNA (m)

sc-152435mGene SilencingN/A0
(0)

PRAME like-6 shRNA Plasmid (m)

sc-152435-SHmGene SilencingPuromycin0
(0)

PRAME like-6 shRNA (m) Lentiviral Particles

sc-152435-VmGene SilencingPuromycin0
(0)

PRAMEF6 siRNA (m)

sc-151593mGene SilencingN/A0
(0)

PRAMEF6 shRNA Plasmid (m)

sc-151593-SHmGene SilencingPuromycin0
(0)

PRAMEF6 shRNA (m) Lentiviral Particles

sc-151593-VmGene SilencingPuromycin0
(0)

PRAME like-7 siRNA (m)

sc-152436mGene SilencingN/A0
(0)

PRAME like-7 shRNA Plasmid (m)

sc-152436-SHmGene SilencingPuromycin0
(0)

PRAME like-7 shRNA (m) Lentiviral Particles

sc-152436-VmGene SilencingPuromycin0
(0)

PRAMEF8 siRNA (h)

sc-76235hGene SilencingN/A0
(0)

PRAMEF8 shRNA Plasmid (h)

sc-76235-SHhGene SilencingPuromycin0
(0)

PRAMEF8 shRNA (h) Lentiviral Particles

sc-76235-VhGene SilencingPuromycin0
(0)

PRAMEF8 siRNA (m)

sc-108961mGene SilencingN/A0
(0)

PRAMEF8 shRNA Plasmid (m)

sc-108961-SHmGene SilencingPuromycin0
(0)

PRAMEF8 shRNA (m) Lentiviral Particles

sc-108961-VmGene SilencingPuromycin0
(0)

PRAMEF10 siRNA (h)

sc-76217hGene SilencingN/A0
(0)

PRAMEF10 shRNA Plasmid (h)

sc-76217-SHhGene SilencingPuromycin0
(0)

PRAMEF10 shRNA (h) Lentiviral Particles

sc-76217-VhGene SilencingPuromycin0
(0)

PRAMEF12 siRNA (h)

sc-76221hGene SilencingN/A0
(0)

PRAMEF12 shRNA Plasmid (h)

sc-76221-SHhGene SilencingPuromycin0
(0)

PRAMEF12 shRNA (h) Lentiviral Particles

sc-76221-VhGene SilencingPuromycin0
(0)

PRAMEF12 siRNA (m)

sc-76222mGene SilencingN/A0
(0)

PRAMEF12 shRNA Plasmid (m)

sc-76222-SHmGene SilencingPuromycin0
(0)

PRAMEF12 shRNA (m) Lentiviral Particles

sc-76222-VmGene SilencingPuromycin0
(0)

PRAMEF13 siRNA (h)

sc-106971hGene SilencingN/A0
(0)

PRAMEF13 shRNA Plasmid (h)

sc-106971-SHhGene SilencingPuromycin0
(0)

PRAMEF13 shRNA (h) Lentiviral Particles

sc-106971-VhGene SilencingPuromycin0
(0)

PRAMEF14 siRNA (h)

sc-106439hGene SilencingN/A0
(0)

PRAMEF14 shRNA Plasmid (h)

sc-106439-SHhGene SilencingPuromycin0
(0)

PRAMEF14 shRNA (h) Lentiviral Particles

sc-106439-VhGene SilencingPuromycin0
(0)

PRAME CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PRAME CRISPR/Cas9 KO Plasmid (h)

sc-404682Gene Knockouth0
(0)

PRAME HDR Plasmid (h)

sc-404682-HDRHomology Directed Repairh0
(0)

PRAMEF6 CRISPR/Cas9 KO Plasmid (h)

sc-417298Gene Knockouth0
(0)

PRAMEF7 CRISPR/Cas9 KO Plasmid (h)

sc-416053Gene Knockouth0
(0)

PRAMEF7 HDR Plasmid (h)

sc-416053-HDRHomology Directed Repairh0
(0)

PRAME CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PRAME CRISPR Activation Plasmid (h)

sc-404682-ACTGene Activationh0
(0)

PRAME CRISPR Activation Plasmid (h2)

sc-404682-ACT-2Gene Activationh0
(0)

PRAME Lentiviral Activation Particles (h)

sc-404682-LACGene Activationh0
(0)