Date published: 2026-4-24

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β1 Tubulin Activators

β1 Tubulin is a fundamental component of microtubules, which are structural elements within the cell that are essential for a variety of cellular functions, including maintaining cell shape, enabling intracellular transport, and facilitating cell division. As a class I beta-tubulin, it is one of the most common isotypes within the beta-tubulin family and is expressed ubiquitously across different cell types.Microtubules are dynamic polymers made of alpha and beta-tubulin dimers. The precise assembly and disassembly of these dimers are regulated by various cellular signals and are critical for the microtubule's role in mitosis and cell motility. β1 Tubulin plays a key role in these processes by integrating into the microtubule structure and responding to the cellular machinery that controls microtubule dynamics.

Mutations or alterations in β1 Tubulin expression can have profound effects on cell function and have been associated with a range of pathological conditions, including neurodegenerative diseases and cancer. In cancer, for instance, β1 Tubulin is often a target of chemo drugs that aim to disrupt microtubule function and thus inhibit cell division.Due to its essential role in microtubule formation and function, β1 Tubulin is also a subject of interest in the development of drugs designed to modulate microtubule dynamics for purposes. Its expression and regulation are therefore of significant importance in both the understanding of cell biology and the development of interventions for diseases involving cell proliferation and movement.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

Stabilizes microtubules, which may trigger a feedback mechanism to adjust tubulin levels.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$59.00
$85.00
$143.00
$247.00
38
(2)

Disrupts microtubules, which could induce the cell to produce more tubulin to restore equilibrium.

Epothilone B, Synthetic

152044-54-7sc-203944
2 mg
$176.00
(0)

A microtubule-stabilizing agent, possibly causing cells to upregulate tubulin synthesis.

Podophyllotoxin

518-28-5sc-204853
100 mg
$84.00
1
(1)

Inhibits microtubule assembly; cells might compensate by increasing tubulin production.

Vinblastine

865-21-4sc-491749
sc-491749A
sc-491749B
sc-491749C
sc-491749D
10 mg
50 mg
100 mg
500 mg
1 g
$102.00
$235.00
$459.00
$1749.00
$2958.00
4
(0)

Disrupts microtubule assembly, which may lead to increased expression of tubulin isotypes.

Cytochalasin D

22144-77-0sc-201442
sc-201442A
1 mg
5 mg
$165.00
$486.00
64
(4)

Affects actin filaments, potentially triggering a compensatory increase in microtubule components like β1 Tubulin.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$94.00
$213.00
33
(5)

Antimetabolite that can disrupt cell division, potentially affecting tubulin expression.

Withaferin A

5119-48-2sc-200381
sc-200381A
sc-200381B
sc-200381C
1 mg
10 mg
100 mg
1 g
$130.00
$583.00
$4172.00
$20506.00
20
(1)

A steroidal lactone that has been shown to bind to tubulin and affect its dynamics, potentially increasing its expression.