Angptl1 Activators
Angptl1 Activators are a class of chemical compounds that directly or indirectly enhance the functional activity of Angptl1. Angptl1, also known as Angiopoietin-like 1, is involved in various cellular processes such as angiogenesis, vasodilation, and vascular remodeling. Compounds like Sphingosine 1-phosphate (S1P), Nitric Oxide (NO), Prostaglandin E2 (PGE2), and Lysophosphatidic acid (LPA) can enhance the functional activity of Angptl1 by promoting processes that require Angpt1, such as angiogenesis and vasodilation. These processes are crucial for the normal functioning of the circulatory system, and Angptl1 plays a key role in their regulation.
In addition, compounds like Forskolin, Thrombin, Histamine, Eicosapentaenoic acid (EPA), Adenosine, and Phorbol 12-myristate 13-acetate (PMA) also enhance the functional activity of Angptl1 by influencing cellular processes that require Angptl1. For example, Forskolin enhances the activity of adenylyl cyclase, leading to an increase in intracellular levels of cAMP, which can stimulate processes that require Angptl1, such as vasodilation and angiogenesis. Thrombin, on the other hand, enhances the functional activity of Angptl1 by promoting coagulation and subsequent vascular remodeling, both of which require Angptl1.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P is a bioactive lipid mediator that plays a crucial role in angiogenesis. It can enhance Angptl1 activity by promoting angiogenesis, a process that requires Angptl1. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 is a prostaglandin that is involved in vasodilation and inflammation. It can enhance the functional activity of Angptl1 by promoting vasodilation and inflammatory responses, both of which require the involvement of Angptl1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a compound that activates adenylyl cyclase and increases intracellular levels of cAMP. This can enhance the functional activity of Angptl1 by promoting cellular processes that rely on cAMP, including vasodilation and angiogenesis. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $98.00 $341.00 | 50 | |
LPA is a bioactive lipid that acts as a potent mitogen in various systems. It can enhance Angptl1 activity by promoting cell proliferation and migration, processes which are crucial for angiogenesis and thus require Angptl1. | ||||||
Thrombin from human plasma | 9002-04-4 | sc-471713 | 100 U | $235.00 | ||
Thrombin is an enzyme that converts soluble fibrinogen into insoluble strands of fibrin. It can enhance the functional activity of Angptl1 by promoting coagulation and subsequent vascular remodeling, both of which require Angptl1. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine is a compound released by cells in response to injury and in allergic and inflammatory reactions. It can enhance the functional activity of Angptl1 by promoting vasodilation and permeability of blood vessels, processes that require Angptl1. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $104.00 $431.00 | ||
EPA is an omega-3 fatty acid that plays a role in reducing inflammation. It can enhance the functional activity of Angptl1 as it requires Angptl1 for mediating its anti-inflammatory effects. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine is a purine nucleoside that regulates many physiological processes including vasodilation. It can enhance the functional activity of Angptl1 by promoting vasodilation, a process that requires Angptl1. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a compound that activates protein kinase C (PKC), which regulates signal transduction pathways implicated in cell growth and differentiation. PMA can enhance the functional activity of Angptl1 by activating PKC, which can stimulate Angptl1-dependent vascular remodeling pathways. | ||||||