ACCÈS RAPIDE AUX LIENS
Xinα, also known as CMYA1 (Cardiomyopathy-associated protein 1) or XIRP1 (xin actin-binding repeat containing 1), is a 1,843 amino acid protein that functions to protect Actin filaments from depolymerization. co-localized to the cell junction with actin stress fibers, Xinα contains 15 Xin repeats and interacts with several proteins including β-catenin, Filamin and VASP (vasodilator-stimulated phosphoprotein). The Xin repeats with the protein are thought to stabilize actin-based cytoskeletons and may help to crosslink microfilaments with actin networks. Xinα shares 78% similarity with its mouse counterpart and is expressed in the heart as three alternatively spliced isoforms designated A, B and C. In mice, Xinα is essential for proper heart tube formation and correct cardiac looping, suggesting that the human homolog may have similar functions.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Xinα (41) | sc-136123 | 50 µg/0.5 ml | $316.00 |