

ACCÈS RAPIDE AUX LIENS
Xinα, also known as CMYA1 (Cardiomyopathy-associated protein 1) or XIRP1 (xin actin-binding repeat containing 1), is a 1,843 amino acid protein that functions to protect Actin filaments from depolymerization. co-localized to the cell junction with actin stress fibers, Xinα contains 15 Xin repeats and interacts with several proteins including β-catenin, Filamin and VASP (vasodilator-stimulated phosphoprotein). The Xin repeats with the protein are thought to stabilize actin-based cytoskeletons and may help to crosslink microfilaments with actin networks. Xinα shares 78% similarity with its mouse counterpart and is expressed in the heart as three alternatively spliced isoforms designated A, B and C. In mice, Xinα is essential for proper heart tube formation and correct cardiac looping, suggesting that the human homolog may have similar functions.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Xinα (41) | sc-136123 | 50 µg/0.5 ml | $316.00 |