Anticorps WHIP (A-8): sc-376438
- L'Anticorps WHIP (A-8) est un monoclonal de souris IgG2b κ, cité dans 2 publications, fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 1-27 au niveau N-terminus de WHIP d'origine human
- recommandé pour la détection de WHIP d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-376438 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps WHIP (A-8) pour les applications WB et IHC(P). Ces réactifs sont désormais proposés en lots avec l'anticorps WHIP (A-8)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Werner's syndrome is an inherited, autosomal recessive disorder that is characterized by premature aging and commonly results in cancer. WHIP, also known as WRNIP1 (Werner helicase-interacting protein 1) is a ubiquitously expressed member of the AAA ATPase family that is involved in the regulation of DNA synthesis. Localized to the nucleus, WHIP acts as a modulator for initiation events during DNA polymerase-mediated DNA synthesis and, through its ATPase activity, can detect DNA damage or arrested replication forks. WHIP is found in granular structures within the nucleus, where it interacts with the N-terminal domain of WRN, the protein product of the gene responsible for Werner's syndrome. Due to its close association with WRN, WHIP is thought to be involved in the aging process and thus may play a role in the development of Werner's syndrome. Four isoforms of WHIP are produced due to alternative splicing events.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps WHIP (A-8) | sc-376438 | 200 µg/ml | $316.00 | |||
WHIP (A-8): m-IgG Fc BP-HRP Kit | sc-537987 | 200 µg Ab; 10 µg BP | $354.00 | |||
WHIP (A-8): m-IgGκ BP-HRP Kit | sc-535490 | 200 µg Ab; 40 µg BP | $354.00 | |||
WHIP (A-8): m-IgG2b BP-HRP Kit | sc-549909 | 200 µg Ab; 10 µg BP | $354.00 | |||
WHIP (A-8) peptide neutralisant | sc-376438 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps WHIP (A-8) X | sc-376438 X | 200 µg/0.1 ml | $316.00 |