Anticorps UNC45A (F-7): sc-390231
- L'Anticorps UNC45A (F-7) est un monoclonal de souris mouse IgM κ (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 923-944 au niveau C-terminus de UNC45A d'origine human
- recommandé pour la détection de UNC45A d'origine mouse, rat et human par WB, IP, IF et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire UNC45A (F-7). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
UNC45A (unc-45 homolog A), also known as SMAP1 (Smooth muscle cell-associated protein 1) or GCUNC45, is a 944 amino acid protein that localizes to the perinuclear region of the cytoplasm and contains three TPR repeats. Expressed in spinal cord, bone marrow, peripheral blood leukocytes, trachea, stomach and adrenal gland, UNCA45A functions as a chaperone for HSP 90, effectively facilitating the association of HSP 90 with PR (progesterone receptor). Additionally, UNC45A is thought to be necessary for proper folding of Myosin and is required for normal myotube formation during muscle cell development, thereby playing an important role in muscle formation. Overexpression of UNC45A is associated with rapid cell proliferation and motility, especially that observed in ovarian cancer, suggesting a role for UNC45A in tumorigenesis. Multiple isoforms of UNC45A exist due to alternative splicing events.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps UNC45A (F-7) | sc-390231 | 200 µg/ml | $316.00 | |||
UNC45A (F-7) peptide neutralisant | sc-390231 P | 100 µg/0.5 ml | $68.00 |