Anticorps UCKL1 (SY-16): sc-100636
- L'Anticorps UCKL1 (SY-16) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 50 µg/0.5 ml
- dirigé contre la UCKL1 recombinante d'origine human
- recommandé pour la détection de UCKL1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire UCKL1 (SY-16). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
UCKL1 (uridine-cytidine kinase 1-like 1), also known as UCK1L, URKL1 or F538, is a ubiquitously expressed 548 amino acid member of the uridine kinase family. Localized to the cytoplasm and translocated to the nucleus via interaction with EBV EBNA-3A (an Epstein-Barr nuclear antigen), UCKL1 is thought to participate in pyrimidine metabolism by accumulating UTP and CTP, both of which are needed for cell proliferation and blast transformation. UCKL1 contains an N-terminal ATP/GTP-binding site and, once relocated to the nucleus, becomes part of the ATP-dependent ribonucleotide salvage pathway that catalytically converts UTP and CTP to UMP and CMP, respectively. In addition, UCKL1 functions as a substrate for the E3 ligase NKLAM, thereby causing the ubiquitin-mediated degradation of UCKL1. Three isoforms of UCKL1 are expressed due to alternative splicing events.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps UCKL1 (SY-16) | sc-100636 | 50 µg/0.5 ml | $316.00 |