Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBE2S (ubiquitin-conjugating enzyme E2S), also known as EPF5 or E2EPF, is a 222 amino acid protein that belongs to the E2 family of ubiquitin-conjugating enzymes. Involved in the protein degradation pathway, UBE2S catalyzes the ATP-dependent attachment of ubiquitin (Ub) to target proteins, thereby tagging them for subsequent destruction by the proteasome. UBE2S is thought to increase the rate of tumor cell proliferation, invasion and metastasis through the VHL (von Hippel-Lindau) pathway, suggesting a role for UBE2S in carcinogenesis.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps UBE2S (F-10) | sc-398339 | 200 µg/ml | $316.00 | |||
UBE2S (F-10): m-IgG Fc BP-HRP Kit | sc-540934 | 200 µg Ab; 10 µg BP | $354.00 | |||
UBE2S (F-10) peptide neutralisant | sc-398339 P | 100 µg/0.5 ml | $68.00 |