Anticorps UBE2J1 (18-Y): sc-100624
- L'Anticorps UBE2J1 (18-Y) est un monoclonal de souris IgG2a κ, cité dans 5 publications, fourni en 100 µg/ml
- dirigé contre la UBE2J1 recombinante d'origine human
- recommandé pour la détection de UBE2J1 d'origine mouse, rat et human par WB, IP et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire UBE2J1 (18-Y). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J1 (Ubiquitin-conjugating enzyme E2 J1), also known as Ubc6p, CGI-76, NCUBE1, HSPC153 or HSPC205, is a 318 amino acid single-pass type IV membrane protein that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J1 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps UBE2J1 (18-Y) | sc-100624 | 100 µg/ml | $333.00 |