ACCÈS RAPIDE AUX LIENS
TRIM (T-cell receptor interacting molecule) is a novel transmembrane adaptor protein which associates and comodulates with the TCR-CD3z complex in human T lymphocytes and T cell lines. TRIM is a type III transmembrane protein that contains an 8-amino acid extracellular domain and an intracellular domain that contains four potential phosphorylation sites and 8 tyrosine residues, at least 3 of which may be involved in SH2-mediated interactions with other signaling proteins. The human TRIM gene maps to chromosome 3q13, which is a susceptibility locus for rheumatoid arthritis and is in proximity to the CD28, CD86, and CD80 genes, all of which encode T-cell costimulatory molecules. TRIM is expressed in T-cells and natural killer cells, but not in B cells or monocytic cells. In T-cells, TRIM localizes to the cell membrane and associates with CD3z and CD3e.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TRIM (G-10) | sc-393658 | 200 µg/ml | $316.00 | |||
TRIM (G-10): m-IgG Fc BP-HRP Kit | sc-538273 | 200 µg Ab; 10 µg BP | $354.00 | |||
TRIM (G-10): m-IgGκ BP-HRP Kit | sc-535851 | 200 µg Ab; 40 µg BP | $354.00 | |||
TRIM (G-10): m-IgG1 BP-HRP Kit | sc-545616 | 200 µg Ab; 20 µg BP | $354.00 |