TREML2 Antibody (G-12): sc-390343
- TREML2 Antibody (G-12) is a mouse monoclonal IgG1 κ TREML2 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 248-259 within an extracellular domain of TREML2 of mouse origin
- TREML2 Antibody (G-12) is recommended for detection of TREML2 of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
- Anti-TREML2 Antibody (G-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TREML2 Antibody (G-12) for WB and IHC(P) applications. These reagents are now offered in bundles with TREML2 Antibody (G-12) (see ordering information below).
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TREML2 Antibody (G-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects TREML2 protein of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). anti-TREML2 antibody (G-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TREML2, also known as triggering receptor expressed on myeloid cells-like 2, C6orf76, or TLT2, is a 321 amino acid single-pass type I membrane protein characterized by one immunoglobulin-like V-type domain. TREML2 is primarily located on the surface of immune cells, including B cells and monocytes, where TREML2 plays a crucial role in modulating immune responses. TREML2 interaction with specific ligands can influence both innate and adaptive immunity, making TREML2 an important target for understanding immune system dynamics and potential therapeutic interventions. TREML2 gene is situated on human chromosome 6, a region associated with various diseases, including certain cancers and neurological disorders, highlighting TREML2′s significance in both health and disease contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TREML2 Antibody (G-12) References:
- The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. | Allcock, RJ., et al. 2003. Eur J Immunol. 33: 567-77. PMID: 12645956
- Trem-like transcript 2 is expressed on cells of the myeloid/granuloid and B lymphoid lineage and is up-regulated in response to inflammation. | King, RG., et al. 2006. J Immunol. 176: 6012-21. PMID: 16670310
- Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis. | Wiersinga, WJ., et al. 2007. J Infect Dis. 196: 1707-16. PMID: 18008257
- Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses. | Hashiguchi, M., et al. 2008. Proc Natl Acad Sci U S A. 105: 10495-500. PMID: 18650384
- Triggering Receptor Expressed on Myeloid Cells (TREM) family and the application of its antagonists. | Molloy, EJ. 2009. Recent Pat Antiinfect Drug Discov. 4: 51-6. PMID: 19149696
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TREML2 Antibody (G-12) | sc-390343 | 200 µg/ml | $322.00 | |||
TREML2 Antibody (G-12): m-IgG Fc BP-HRP Bundle | sc-530129 | 200 µg Ab; 10 µg BP | $361.00 | |||
TREML2 Antibody (G-12): m-IgGκ BP-HRP Bundle | sc-523498 | 200 µg Ab, 40 µg BP | $361.00 | |||
TREML2 Antibody (G-12): m-IgG1 BP-HRP Bundle | sc-543882 | 200 µg Ab; 20 µg BP | $361.00 | |||
TREML2 Antibody (G-12) AC | sc-390343 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TREML2 Antibody (G-12) HRP | sc-390343 HRP | 200 µg/ml | $322.00 | |||
TREML2 Antibody (G-12) FITC | sc-390343 FITC | 200 µg/ml | $336.00 | |||
TREML2 Antibody (G-12) PE | sc-390343 PE | 200 µg/ml | $349.00 | |||
TREML2 Antibody (G-12) Alexa Fluor® 488 | sc-390343 AF488 | 200 µg/ml | $364.00 | |||
TREML2 Antibody (G-12) Alexa Fluor® 546 | sc-390343 AF546 | 200 µg/ml | $364.00 | |||
TREML2 Antibody (G-12) Alexa Fluor® 594 | sc-390343 AF594 | 200 µg/ml | $364.00 | |||
TREML2 Antibody (G-12) Alexa Fluor® 647 | sc-390343 AF647 | 200 µg/ml | $364.00 | |||
TREML2 Antibody (G-12) Alexa Fluor® 680 | sc-390343 AF680 | 200 µg/ml | $364.00 | |||
TREML2 Antibody (G-12) Alexa Fluor® 790 | sc-390343 AF790 | 200 µg/ml | $364.00 | |||
TREML2 (G-12) Neutralizing Peptide | sc-390343 P | 100 µg/0.5 ml | $69.00 |