Anti-L'anticorps Tom40 D-2 est un monoclonal IgG1 κ L'Anticorps Tom40, cité dans 26 publications, fourni en 200 µg/ml
dirigé contre les acides aminés 62-361 de Tom40 d'origine human
Anti-L'Anticorps Tom40 (D-2) est recommandé pour la détection de Tom40 d'origine mouse, rat et human par WB, IP, IF et ELISA
Anti-L'Anticorps Tom40 (D-2) est disponible conjugué à l'agarose pour IP; à l'HRP pour WB, IHC(P) et ELISA; et soit à la phycoerythrin ou FITC pour IF, IHC(P) et FCM
aussi disponible conjugué à l'Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 ou Alexa Fluor® 647 pour WB (RGB), IF, IHC(P) et FCM
aussi disponible conjugué à l'Alexa Fluor® 680 ou Alexa Fluor® 790 pour WB (NIR), IF et FCM
Contactez notre Service Technique (ou votre Distributeur local) pour plus d'informations pour recevoir un échantillon GRATUIT de 10 µg de Tom40 (D-2): sc-365467.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for Tom40 Antibody (D-2) for WB applications. This reagent is now offered in a bundle with Tom40 Antibody (D-2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Tom40 Antibody (D-2) is a high quality monoclonal Tom40 antibody (also designated Translocase Of Outer Mitochondrial Membrane 40 antibody, C19orf1 antibody, PEREC1 antibody, Translocase Of Outer Membrane 40 KDa Subunit Homolog antibody, Mitochondrial Import Receptor Subunit TOM40 Homolog antibody, Translocase Of Outer Mitochondrial Membrane 40 Homolog (Yeast) antibody, Translocase Of Outer Mitochondrial Membrane 40 Homolog antibody, or Mitochondrial Outer Membrane Protein antibody) suitable for the detection of the Tom40 protein of mouse, rat and human origin. Tom40 Antibody (D-2) is available as both the non-conjugated anti-Tom40 antibody form, as well as multiple conjugated forms of anti-Tom40 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The mitochondrial preprotein translocases of the outer membrane (Tom) is a multisubunit protein complex that facilitates the import of nucleus-encoded precursor proteins across the mitochondrial outer membrane. The Tom machinery consists of import receptors for the initial binding of cytosolically synthesized preproteins and a general import pore (GIP) for the membrane translocation of various preproteins into the mitochondria. The import receptors include Tom20 and Tom22, which form a heteromeric receptor complex that initiates the insertion of newly synthesized proteins into the outer membrane and then directs the precursor protein into the GIP. In yeast, Tom22 is the essential component of the import receptor complex as it functions as both a receptor for the preproteins and serves as a docking point for both Tom20 and the GIP. Tom22 directly associates with Tom40, the major component of the GIP, and thereby forms a stable interaction between the two core complexes to facilitate the fluid movement of preproteins into the mitochondria. The insertion of Tom40 into the Tom machinery requires the initial binding of Tom40 to Tom20 and leads to the efficient incorporation of Tom40 precursors into preexisting Tom complexes (2,8)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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