Transmembrane protein containing epidermal growth factor and two follistatin domains proteins (TMEFF1 and TMEFF2) are single-pass type 1 membrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. TMEFF2, which also is designated hyperplastic polyposis protein 1 (HPP1) or tomoregulin (TR), may act as a survival factor for mesencephalic and hippocampal neurons. It is highly expressed in brain, prostate and spinal cord, but can also be detected in colon and stromal cells of normal colonic mucosa. TMEFF2, which is highly glycosylated, is down-regulated in tumor cell lines as a result of methylations in its 5' region.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TMEFF2 (J4B6) | sc-135812 | 50 µg/0.5 ml | $316.00 |