In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Human TFIIE consists of two subunits, α and β. The structure of TFIIE appears to be a heterotetramer (α2β2); both subunits are required for optimal basal-level transcription.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TFIIE-α (B-7) | sc-374014 | 200 µg/ml | $316.00 | |||
TFIIE-α (B-7): m-IgG Fc BP-HRP Kit | sc-540413 | 200 µg Ab; 10 µg BP | $354.00 | |||
TFIIE-α (B-7): m-IgG1 BP-HRP Kit | sc-542103 | 200 µg Ab; 20 µg BP | $354.00 | |||
TFIIE-α (B-7) peptide neutralisant | sc-374014 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps TFIIE-α (B-7) X | sc-374014 X | 200 µg/0.1 ml | $316.00 |