Plastins (fimbrins) are members of a family of Actin-binding proteins that exhibit a tissue-specific expression pattern. Both L- and T-Plastin have been shown to be involved in cytoskeletal reorganization. L-Plastin, which is specifically expressed in hematopoietic cell lineages, has been proposed to be involved in the control of cell adhesion and motility. It is frequently expressed in cell lines derived from mammary solid tumors and is implicated in cancer invasion and metastasis. L-Plastin is also expressed in the majority of human cancer cell lines that are derived from various types of solid tumors. Additionally, L-Plastin is involved in regulating of leukocyte adhesion, and the phosphorylation of L-Plastin is implicated in modulating integrin regulation signaling pathways. T-Plastin is unique in that it is expressed in many types of tissues and notably absent in leukocytes.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps T-Plastin (A-8) | sc-166223 | 200 µg/ml | $316.00 | |||
T-Plastin (A-8): m-IgG Fc BP-HRP Kit | sc-537458 | 200 µg Ab; 10 µg BP | $354.00 | |||
T-Plastin (A-8): m-IgGκ BP-HRP Kit | sc-534731 | 200 µg Ab; 40 µg BP | $354.00 | |||
T-Plastin (A-8): m-IgG2b BP-HRP Kit | sc-549875 | 200 µg Ab; 10 µg BP | $354.00 | |||
T-Plastin (A-8) peptide neutralisant | sc-166223 P | 100 µg/0.5 ml | $68.00 |