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Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 8, also known as STX8 or CARB, is a 236 amino acid single-pass type IV membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the Syntaxin family. Highly expressed in liver, brain, kidney, lung, placenta, spleen, pancreas and skeletal muscle, Syntaxin 8 functions in the early secretory pathway as a vesicle trafficking protein that shuttles proteins from the cis-Golgi membrane to the endoplasmic reticulum (ER). In addition, Syntaxin 8 associates with Syntaxin 7, v-SNARE Vti1p and endobrevin to form a SNARE complex that plays a role in the homotypic fusion of late endosomes.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Syntaxin 8 (48) | sc-136092 | 50 µg/0.5 ml | $316.00 |