Anticorps Synaptotagmin IV (28-N): sc-101302
- L'Anticorps Synaptotagmin IV (28-N) est un monoclonal de souris IgG3 (chaîne légère kappa) fourni en 100 µg/ml
- dirigé contre la Synaptotagmin IV recombinante d'origine human
- recommandé pour la détection de Synaptotagmin IV d'origine human par WB, IP, IF et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Synaptotagmin IV (28-N). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Synaptotagmin IV (28-N) | sc-101302 | 100 µg/ml | $333.00 |