Anticorps Superoxide Dismutase 2/SOD2 (24): sc-130346
- L'Anticorps Superoxide Dismutase 2/SOD2 (24) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
- dirigé contre la SOD-2 recombinante d'origine human
- recommandé pour la détection de SOD-2 d'origine human par WB, IP et ELISA
- Voir Superoxide Dismutase 2/SOD2 (E-10): sc-137254 pour d'autres anticorps conjugués Superoxide Dismutase 2/SOD2, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour Superoxide Dismutase 2/SOD2 Antibody (24) for WB applications. Ces réactifs sont désormais proposés en lots avec Superoxide Dismutase 2/SOD2 Antibody (24)(voir les informations de commande ci-dessous).
The superoxide dismutase family is composed of three metalloenzymes (SOD-1, SOD-2 and SOD-3) that catalyze the oxido-reduction of reactive oxygen species (ROS) such as superoxide anion. The SOD-2 precursor is a 222 amino acid protein that is encoded by nuclear chromatin, synthesized in the cytosol and imported posttranslationally into the mitochondrial matrix. Unlike SOD-1, which is a homodimeric cytosolic Cu-Zn enzyme, SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer's disease, Parkinson's disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle. Polymorphisms in the SOD-2 gene have also been implicated in nonfamilial, idiopathic, dilated cardiomyopathy in humans.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Superoxide Dismutase 2/SOD2 (24) | sc-130346 | 200 µg/ml | $316.00 | |||
Superoxide Dismutase 2/SOD2 (24): m-IgG Fc BP-HRP Kit | sc-539817 | 200 µg Ab; 10 µg BP | $354.00 | |||
Superoxide Dismutase 2/SOD2 (24): m-IgG1 BP-HRP Kit | sc-541728 | 200 µg Ab; 20 µg BP | $354.00 |