Anticorps SNX2 (13): sc-136072
- L'anticorps SNX2 13 est un monoclonal IgG1 de souris, cité dans 3 publications, fourni en 50 µg/0.5 ml
- dirigé contre les acides aminés 15-137 de SNX2 d'origine human
- recommandé pour la détection de SNX2 d'origine mouse, rat et human par WB, IP et IF; également réactif avec d'autres espèces, dont canine
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire SNX2 (13). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor and facilitate its transport to lysosome, thereby contributing to the degradation of the receptor. SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes and they likewise associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multi-subunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SNX2 (13) | sc-136072 | 50 µg/0.5 ml | $316.00 |