Date published: 2025-9-7

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Anticorps SmcX (C-1): sc-365860

3.0(2)
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Fiches techniques
  • L'Anticorps SmcX (C-1) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 1462-1560 situés au niveau C-terminus de SmcX d'origine human
  • recommandé pour la détection de SmcX d'origine human par WB, IP, IF et ELISA
  • Réactifs TransCruz pour une application en ChIP (sc-365860 X, 200 µg/0.1 ml)
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire SmcX (C-1). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    SmcX, also known as JARID1C (jumonji, AT rich interactive domain 1C), MRXJ, KDM5C or XE169, is a nuclear protein that contains one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers and belongs to the JARID1 histone demethylase family. Expressed ubiquitously with highest expression in brain and skeletal muscle, SmcX functions as a histone demethylase that removes methyl groups from lysine residues on Histone H3, thereby playing a role in the histone code, as well as transcriptional regulation and chromatin remodeling. SmcX binds iron and α-ketoglutarate as cofactors and can recruit histone deacetylases to neuron silencer elements, thus repressing the transcription of neuronal genes. Defects in the gene encoding SmcX are associated with X-linked mental retardation (XLMR), a condition characterized by cognitive impairment and a low IQ. Multiple isoforms of SmcX are expressed due to alternative splicing events.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps SmcX (C-1)

    sc-365860
    200 µg/ml
    $316.00

    Anticorps SmcX (C-1) X

    sc-365860 X
    200 µg/0.1 ml
    $316.00

    What blocking solution should I use with SmcX (C-1): sc-365860 monoclonal antibody for Western blot?

    Posée par: DefinitelyNotMatt
    Thank you for your question. We recommend blocking with Blotto (either TBS Blotto A: sc-2333 or TBS Blotto B: sc-2335). Our Western blot protocol can be found here: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_9, d_6, h_5CST
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    Rated 1 de 5 de par LOT#F0211 no signal in MCF7 cellsLOT#F0211 no signal in MCF7 cells for western blot
    Date de publication: 2017-01-10
    Rated 5 de 5 de par Good Western blot data of SmcX expression in nonGood Western blot data of SmcX expression in non-transfected and human SmcX transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2014-10-13
    • y_2025, m_9, d_6, h_5
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    Anticorps SmcX (C-1) est évalué 3.0 de 5 de 2.
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