Anticorps SEMA3A (C-1): sc-74555
- L'Anticorps SEMA3A (C-1) est un monoclonal de souris IgG1 κ, cité dans 4 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 103-402 de Semaphorin 3A d'origine human
- recommandé pour la détection de SEMA3A d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- Voir SEMA3A (A-12): sc-74554 pour d'autres anticorps conjugués SEMA3A, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP et m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps SEMA3A (C-1) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps SEMA3A (C-1) (voir Informations pour la commande ci-dessous).
Semaphorins (SEMAs) comprise a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular "semaphorin" domain of approximately 500 amino acids containing 14-16 cysteines, many blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins are known to chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. In addition to their role in axonal guidance, semaphorins have also been associated with the progression of cancer. Many semaphorins bind to the receptors neuropilin and neuropilin-2, thus competing with VEGF for this interaction, which ultimately results in the suppression of angiogenesis. The loss of functional semaphorins to compete with VEGF may play an important role in tumor progression.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SEMA3A (C-1) | sc-74555 | 200 µg/ml | $316.00 | |||
SEMA3A (C-1): m-IgG Fc BP-HRP Kit | sc-539545 | 200 µg Ab; 10 µg BP | $354.00 | |||
SEMA3A (C-1): m-IgG1 BP-HRP Kit | sc-541551 | 200 µg Ab; 20 µg BP | $354.00 |