Date published: 2025-9-8

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Anticorps SAP 62 (4G8): sc-130563

5.0(2)
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Fiches techniques
  • L'Anticorps SAP 62 (4G8) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • soulevé contre SAP 62 extrait de noyaux de foie d'origine rat, avec cartographie de l'épitope au niveau de C-terminus.
  • recommandé pour la détection de the native and denatured form of SAP 62 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG Fc BP-HRP et m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps SAP 62 (4G8) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps SAP 62 (4G8) (voir Informations pour la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    SAP 62, also known as SF3A2 (Splicing factor 3A subunit 2), PRP11, PRPF11 or SF3a66, is a 464 amino acid protein that contains one matrin-type zinc finger and belongs to the SF3A2 family. Localized to the nucleus, SAP 62 is a subunit of the SF3A splicing factor, a heterotrimeric complex comprised of three subunits that act in tandem to mediate the binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. The SF3A complex is necessary for the conversion of 15S U2 snRNP into the active 17S protein that performs directly in pre-mRNA splicing events. Functioning as the second subunit of the complex, SAP 62 interacts with subunit 1 (SAP 114) via its N-terminus while simultaneously binding to 15S U2 snRNP via its zinc finger domain. In addition to its role in RNA splicing, SAP 62 is thought to act independently as a microtubule-binding protein.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps SAP 62 (4G8)

    sc-130563
    200 µg/ml
    $316.00

    SAP 62 (4G8): m-IgG Fc BP-HRP Kit

    sc-539829
    200 µg Ab; 10 µg BP
    $354.00

    SAP 62 (4G8): m-IgG1 BP-HRP Kit

    sc-541736
    200 µg Ab; 20 µg BP
    $354.00

    Can SAP 62 (4G8): sc-130563 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: Cweed
    Thank you for your question. Yes, SAP 62 (4G8): sc-130563 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_9, d_7, h_4CST
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    Rated 5 de 5 de par Performs well in WesternPerforms well in Western, good signal with HeLa, A-431, K-562 and Hep G2 nuclear extracts. -SCBT QC
    Date de publication: 2015-06-05
    Rated 5 de 5 de par Superb immunoperoxidase nuclear and cytoplasmicSuperb immunoperoxidase nuclear and cytoplasmic staining in formalin fixed, paraffin-embedded human cerebellum tissue. -SCBT QC
    Date de publication: 2015-04-11
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    Anticorps SAP 62 (4G8) est évalué 5.0 de 5 de 2.
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