Anticorps SAP 62 (32J-7): sc-101138
- L'Anticorps SAP 62 (32J-7) est un monoclonal de souris IgG2b κ, cité dans 1 publications, fourni en 100 µg/ml
- dirigé contre la SAP 62 recombinante d'origine human
- recommandé pour la détection de SAP 62 d'origine mouse, rat et human par WB, IP, IF et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire SAP 62 (32J-7). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
SAP 62, also known as SF3A2 (Splicing factor 3A subunit 2), PRP11, PRPF11 or SF3a66, is a 464 amino acid protein that contains one matrin-type zinc finger and belongs to the SF3A2 family. Localized to the nucleus, SAP 62 is a subunit of the SF3A splicing factor, a heterotrimeric complex comprised of three subunits that act in tandem to mediate the binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. The SF3A complex is necessary for the conversion of 15S U2 snRNP into the active 17S protein that performs directly in pre-mRNA splicing events. Functioning as the second subunit of the complex, SAP 62 interacts with subunit 1 (SAP 114) via its N-terminus while simultaneously binding to 15S U2 snRNP via its zinc finger domain. In addition to its role in RNA splicing, SAP 62 is thought to act independently as a microtubule-binding protein.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SAP 62 (32J-7) | sc-101138 | 100 µg/ml | $333.00 |