Saccharocarcin B CAS: 158475-33-3
MF: C68H103NO20
MW: 1254.6
An unusual tetronic acid with inhibitory effects on gram positive bacteria.

Saccharocarcin B (CAS 158475-33-3)

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Application: Saccharocarcin B is an unusual tetronic acid with inhibitory effects on gram positive bacteria
Numéro CAS: 158475-33-3
Pureté: >99%
Masse Moléculaire: 1254.6
Formule Moléculaire: C68H103NO20
Pour la Recherche Uniquement. Non conforme pour le Diagnostic ou pour une Utilisation Thérapeutique.
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Saccharocarcin B is an unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcins and versipelostatin which has pronounced activity against Gram positive bacteria and Chlamydia trachomatis. Several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway.

État Physique :
Solid
Dérivé de :
Amycolatopsis
Solubilité :
Soluble in water (limitedly), ethanol, DMSO, methanol, and DMF.
STOCKAGE :
Store at -20° C
Pour la Recherche Uniquement. Non conforme pour le Diagnostic ou pour une Utilisation Thérapeutique.
Numéro MDL :
MFCD14635442

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