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Receptor protein-tyrosine phosphatase α (RPTPα) dephosphorylates and activates Src family tyrosine kinases and influences the regulation of integrin signaling, cell adhesion and growth factor responsiveness. RPTPα contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and constitutively forms dimers in the membrane. The human RPTPα sequence encodes a 793 amino acid protein. Mouse RPTPα precipitated from NIH/3T3 cells is constitutively phosphorylated at Ser 180/Ser 204. RPTPα also serves as a receptor for Helicobacter pylori vacuolating cytotoxin, VacA.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps RPTPα (21) | sc-136188 | 50 µg/0.5 ml | $316.00 |