The Rhesus (Rh) blood group system represents one of the most complex and important systems in humans. Two highly homologous genes, RhD and RhCE (collectively referred to as Rh30 or RhCED), encode the antigens of the Rh blood group system. These tightly linked genes map to human chromosomal position 1p36.11. The RhD gene, which is commonly deleted from a large segment of the population, encodes the most potent blood group immunogen, the D antigen. Rh incompatibility between maternal and fetal blood types results in hemolytic disease of the newborn (HDN), which often results in fetal death. The RhCE gene exists in four allelic forms, and each allele determines the expression of two antigens in Ce, ce, cE, or CE combinations. The RhCED antigens exist as integral membrane proteins which contain 12-transmembrane helices and maintain erythrocyte membrane integrity. The presentation of the Rh antigenic activity requires the formation of a complex between the RhCED antigens and RhAG (Rh50).
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps RhD/CE (3H2011) | sc-71962 | 200 µg/ml | $316.00 | |||
RhD/CE (3H2011): m-IgG Fc BP-HRP Kit | sc-537207 | 200 µg Ab; 10 µg BP | $354.00 | |||
RhD/CE (3H2011): m-IgGκ BP-HRP Kit | sc-534417 | 200 µg Ab; 40 µg BP | $354.00 | |||
RhD/CE (3H2011): m-IgG1 BP-HRP Kit | sc-545077 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps RhD/CE (3H2011) FITC | sc-71962 FITC | 200 µg/ml | $330.00 | |||
Anticorps RhD/CE (3H2011) PE | sc-71962 PE | 200 µg/ml | $343.00 |