Anticorps Rent1 (G-3): sc-166092
- L'Anticorps Rent1 (G-3) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 71-370 situés près de la région N-terminus de Rent1 d'origine human
- recommandé pour la détection de Rent1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-166092 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps Rent1 (G-3) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps Rent1 (G-3)(voir les informations de commande ci-dessous).
In eukaryotes, it is essential to have the ability to detect and degrade transcripts that lack full coding potential. Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential. Rent1, a mammalian ortholog of Upflp, is essential for embryonic viability. Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase. Rent1 protein has nucleic-acid-dependent ATPase activity and 5' to 3' helicase activity. In addition, Rent1 is an RNA-binding protein whose activity is modulated by ATP and directly interacts with Rent2, which is a mammalian homolog of Upf2p. Two mammalian orthologs to Upf3p, Rent3a and Rent3b, are encoded by two separate genes. Rent3b (also known as Rent3X) is encoded by a X-linked gene and localizes primarily to the nucleus, while Rent 1 and Rent 2 localize primarily in the cytoplasm. Specific Rent3 protein interactions with Y14 and spliced mRNA suggest Rent3a and Rent3b serve as a link between splicing and NMD in the cytoplasm.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Rent1 (G-3) | sc-166092 | 200 µg/ml | $316.00 | |||
Rent1 (G-3): m-IgG Fc BP-HRP Kit | sc-537441 | 200 µg Ab; 10 µg BP | $354.00 | |||
Rent1 (G-3): m-IgGκ BP-HRP Kit | sc-534709 | 200 µg Ab; 40 µg BP | $354.00 | |||
Rent1 (G-3): m-IgG1 BP-HRP Kit | sc-545186 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps Rent1 (G-3) X | sc-166092 X | 200 µg/0.1 ml | $316.00 |