Date published: 2025-9-8

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Anticorps RAPGEF6 (BA-17): sc-81919

5.0(3)
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Fiches techniques
  • L'Anticorps RAPGEF6 (BA-17) est un monoclonal de souris IgG2a κ, cité dans 1 publications, fourni en 100 µg/ml
  • dirigé contre la RAPGEF6 recombinante d'origine human
  • recommandé pour la détection de RAPGEF6 d'origine human par WB, IP, IF, IHC(P) et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire RAPGEF6 (BA-17). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

RAPGEF6 (Rap guanine nucleotide exchange factor 6), also known as PDZGEF2 (PDZ domain-containing guanine nucleotide exchange factor 2) or RA-GEF-2, is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps RAPGEF6 (BA-17)

sc-81919
100 µg/ml
$333.00

Can sc-81919: RAPGEF6 (BA-17) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Posée par: Cweed
Thank you for your question. Yes, sc-81919: RAPGEF6 (BA-17) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2017-03-24
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Rated 5 de 5 de par Nice clean band in Hela cellsWe used this antibody for expression detection of RAPGEF6 by western blot. We got a very nice signal around the correct molecular weight in HeLa cells.
Date de publication: 2017-02-09
Rated 5 de 5 de par WB publishable data with human MCF7WB publishable data with human MCF7 - SCBT Publication Review
Date de publication: 2015-03-21
Rated 5 de 5 de par Exceptional immunoperoxidase membrane andExceptional immunoperoxidase membrane and cytoplasmic staining in formalin-fixed, paraffin-embedded human pancreas tissue. -SCBT QC
Date de publication: 2013-02-22
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Anticorps RAPGEF6 (BA-17) est évalué 5.0 de 5 de 3.
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