Cet anticorps polyclonal n'est plus commercialisé. Voir l'anticorps monoclonal Rad52 (F-7) que nous recommandons (données d'échantillonnage indiquées).
Anticorps Rad52 (H-300): sc-8350
- L'anticorps Rad52 H-300 est un polyclonal IgG de lapin fourni en 200 µg/ml
- épitope correspondant aux acides aminés 119-418 situés au niveau C-terminus de Rad52 d'origine human
- Anticorps polyclonal arrêté
Rad52 family members (Rad50, Rad51B/C/D, Rad52, Rad54, MRE11) mediate DNA double-strand break repair (DSBR) for DNA damage that otherwise could cause cell death, mutation or neoplastic transformation. Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands. Rad52 can interact with Rad51. Rad54A of the DEAD-like helicase superfamily binds to double-strand DNA and induces a DNA topological change, which is thought to facilitate homologous DNA pairing, and stimulate DNA recombination. Rad54B of the DEAD-like helicase superfamily binds to double-stranded DNA and displays ATPase activity in the presence of DNA. Rad54B is abundant in testis and spleen, and mutations of this gene occur in primary lymphoma and colon cancer.
Informations pour la commande
Rad52 (F-7): sc-365341 [ Monoclonal recommandé en remplacement de Rad52 (H-300) ]
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Rad52 (F-7) | sc-365341 | 200 µg/ml | $322.00 | |||
Rad52 (F-7): m-IgG Fc BP-HRP Kit | sc-527357 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rad52 (F-7): m-IgG1 BP-HRP Kit | sc-532730 | 200 µg Ab; 20 µg BP | $361.00 | |||
Anticorps Rad52 (F-7) AC | sc-365341 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Anticorps Rad52 (F-7) HRP | sc-365341 HRP | 200 µg/ml | $322.00 | |||
Anticorps Rad52 (F-7) FITC | sc-365341 FITC | 200 µg/ml | $336.00 | |||
Anticorps Rad52 (F-7) PE | sc-365341 PE | 200 µg/ml | $349.00 | |||
Anticorps Rad52 (F-7) Alexa Fluor® 488 | sc-365341 AF488 | 200 µg/ml | $364.00 | |||
Anticorps Rad52 (F-7) Alexa Fluor® 546 | sc-365341 AF546 | 200 µg/ml | $364.00 | |||
Anticorps Rad52 (F-7) Alexa Fluor® 594 | sc-365341 AF594 | 200 µg/ml | $364.00 | |||
Anticorps Rad52 (F-7) Alexa Fluor® 647 | sc-365341 AF647 | 200 µg/ml | $364.00 | |||
Anticorps Rad52 (F-7) Alexa Fluor® 680 | sc-365341 AF680 | 200 µg/ml | $364.00 | |||
Anticorps Rad52 (F-7) Alexa Fluor® 790 | sc-365341 AF790 | 200 µg/ml | $364.00 |