Date published: 2025-9-8

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Anticorps Rabex-5 (D-11): sc-166496

5.0(2)
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Fiches techniques
  • L'Anticorps Rabex-5 (D-11) est un monoclonal de souris IgG1 κ, cité dans 1 publications, fourni en 200 µg/ml
  • soulevée à l'encontre des acides aminés 421-708 correspondant à C-terminus de Rabex-5 d'origine human.
  • recommandé pour la détection de Rabex-5 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG Fc BP-HRP et m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps Rabex-5 (D-11) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps Rabex-5 (D-11) (voir Informations pour la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Rabex-5 (Rab 5 GDP/GTP exchange factor), also known as RABGEF1, RAP1 or RABAPTIN-5-associated exchange factor for Rab 5, is a Rab guanine nucleotide exchange factor. Rabex-5 localizes to the cytoplasm and can associate with early endosomes. It consists of an N-terminal zinc finger domain, a GEF domain, an EET (early endosomal targeting) domain and a coiled-coil domain. The EET domain is important for the association of Rabex-5 with early endosomes and for the activation of Rab 5. Truncated Rabex-5 that is missing its EET domain can still function via an association with RABAPTIN-5. The Rabex-5/RABAPTIN-5 complex can target to early endosomes in a Rab 5-dependent manner through the binding of Rab5-GTP to RABAPTIN-5. In vitro, Rabex-5 exhibits GEF activity on its own, however, its association with RABAPTIN-5 increases its efficiency.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps Rabex-5 (D-11)

sc-166496
200 µg/ml
$316.00

Rabex-5 (D-11): m-IgG Fc BP-HRP Kit

sc-540109
200 µg Ab; 10 µg BP
$354.00

Rabex-5 (D-11): m-IgG1 BP-HRP Kit

sc-541908
200 µg Ab; 20 µg BP
$354.00

Can Rabex-5 (D-11): sc-166496 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Posée par: Professor Griffin
Thank you for your question. Yes, Rabex-5 (D-11): sc-166496 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2017-02-28
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Rated 5 de 5 de par WB publishable data with mouse brainWB publishable data with mouse brain - SCBT Publication Review
Date de publication: 2015-05-09
Rated 5 de 5 de par Beautiful immunofluorescence nucleolar stainingBeautiful immunofluorescence nucleolar staining in formalin-fixed HepG2 cells. -SCBT QC
Date de publication: 2013-07-09
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Anticorps Rabex-5 (D-11) est évalué 5.0 de 5 de 2.
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