Date published: 2025-9-9

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Anticorps Rabex-5 (C-4): sc-166049

4.7(3)
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Fiches techniques
  • L'Anticorps Rabex-5 (C-4) est un monoclonal de souris IgG2b κ, cité dans 2 publications, fourni en 200 µg/ml
  • soulevée contre les acides aminés 421-708 correspondant à C-terminus de Rabex-5 d'origine human.
  • recommandé pour la détection de Rabex-5 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG Fc BP-HRP et m-IgG2b BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps Rabex-5 (C-4) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps Rabex-5 (C-4) (voir Informations pour la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Rabex-5 (Rab 5 GDP/GTP exchange factor), also known as RABGEF1, RAP1 or RABAPTIN-5-associated exchange factor for Rab 5, is a Rab guanine nucleotide exchange factor. Rabex-5 localizes to the cytoplasm and can associate with early endosomes. It consists of an N-terminal zinc finger domain, a GEF domain, an EET (early endosomal targeting) domain and a coiled-coil domain. The EET domain is important for the association of Rabex-5 with early endosomes and for the activation of Rab 5. Truncated Rabex-5 that is missing its EET domain can still function via an association with RABAPTIN-5. The Rabex-5/RABAPTIN-5 complex can target to early endosomes in a Rab 5-dependent manner through the binding of Rab5-GTP to RABAPTIN-5. In vitro, Rabex-5 exhibits GEF activity on its own, however, its association with RABAPTIN-5 increases its efficiency.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps Rabex-5 (C-4)

sc-166049
200 µg/ml
$316.00

Rabex-5 (C-4): m-IgG Fc BP-HRP Kit

sc-539997
200 µg Ab; 10 µg BP
$354.00

Rabex-5 (C-4): m-IgG2b BP-HRP Kit

sc-549764
200 µg Ab; 10 µg BP
$354.00

Can Rabex-5 (C-4): sc-166049 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Posée par: Dr Ninau Qelp
Thank you for your question. Yes, Rabex-5 (C-4): sc-166049 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2017-03-01
  • y_2025, m_9, d_8, h_8CST
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Rated 4 de 5 de par 抗体评论我一年前购买了该抗体,做着效果还行,不过在免疫组化上不够准确,我自己条件弄得不够理想!我需要摸好条件,做出漂亮的结果来!
Date de publication: 2017-03-28
Rated 5 de 5 de par Great immunoperoxidase cytoplasmic and nuclearGreat immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human brain tissue. -SCBT QC
Date de publication: 2015-04-10
Rated 5 de 5 de par Great Western Blot data of RabexGreat Western Blot data of Rabex-5 expression in non-transfected and human Rabex-5 transfected 293T whole cell lysates. -SCBT QC
Date de publication: 2013-09-10
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Anticorps Rabex-5 (C-4) est évalué 4.7 de 5 de 3.
  • y_2025, m_9, d_8, h_8
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