RABAPTIN-5 Antibody (20): sc-136051
- RABAPTIN-5 Antibody (20) is a mouse monoclonal IgG1 provided at 50 µg/500 µl
- raised against amino acids 247-417 of RABAPTIN-5 of human origin
- recommended for detection of RABAPTIN-5 of mouse, rat and human origin by WB, IP and IF; not recommended for IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for RABAPTIN-5 Antibody (20). This work is in progress.
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RABAPTIN-5 Antibody (20) is a mouse monoclonal IgG1 antibody that detects RABAPTIN-5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). RABAPTIN-5 plays a crucial role in the endocytic pathway, particularly in the fusion of early endosomes, which is essential for the proper trafficking and processing of cellular materials. RABAPTIN-5 is characterized by its coiled-coil structure, which facilitates interaction with Rab 5, a key regulator of endocytic transport localized to the plasma membrane and early endosomes. The coiled-coil domain of RABAPTIN-5 allows formation of oligomeric structures that are vital for function in membrane docking and fusion processes. Disruption of RABAPTIN-5 function can lead to significant impairments in endosomal trafficking, highlighting importance in maintaining cellular homeostasis and the overall efficiency of intracellular transport mechanisms. Anti-RABAPTIN-5 antibody (20) is an invaluable tool for researchers studying the dynamics of endocytosis and the molecular interactions that govern vesicular transport in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RABAPTIN-5 Antibody (20) | sc-136051 | 50 µg/500 µl | $322.00 |