Anticorps Rab 3 GAP p130 (G-5): sc-393745
- L'Anticorps Rab 3 GAP p130 (G-5) est un monoclonal de souris IgG3 (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 917-924 près de C-terminus de Rab 3 GAP p130 d'origine human
- recommandé pour la détection de Rab 3 GAP p130 d'origine human par WB, IP, IF et ELISA
- m-IgG3 BP-HRP est le réactif de détection secondaire préféré pour Rab 3 GAP p130 Anticorps (G-5) pour les applications WB. Ce réactif est désormais proposé dans un ensemble avec Rab 3 GAP p130 Anticorps (G-5)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab 3 GAP p130, also known as Rab3 GTPase-activating protein catalytic subunit, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters. Existing as two alternatively spliced isoforms, the Rab 3 GAP p130 gene is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish and fruit fly, and maps to human chromosome 2q21.3.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Rab 3 GAP p130 (G-5) | sc-393745 | 200 µg/ml | $316.00 | |||
Rab 3 GAP p130 (G-5): m-IgG3 BP-HRP Kit | sc-550495 | 200 µg Ab; 40 µg BP | $354.00 | |||
Rab 3 GAP p130 (G-5) peptide neutralisant | sc-393745 P | 100 µg/0.5 ml | $68.00 |