Date published: 2025-9-9

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Anticorps PTPMT1 (B-12): sc-390947

5.0(2)
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Fiches techniques
  • L'Anticorps PTPMT1 (B-12) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 87-127 dans une région interne de PTPMT1 d'origine human
  • recommandé pour la détection de PTPMT1 d'origine human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps PTPMT1 (B-12) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps PTPMT1 (B-12) (voir Informations pour la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Protein tyrosine phosphatases, or PTPs, are type I transmembrane proteins, membrane associated proteins or proteins localized in nuclei. Examples of transmembrane PTPs are LAR, PTPα, PTPβ, PTPγ, PTPδ, PTPe, PTPΩ, PTPκ and PTPµ. Transmembrane PTPs play diverse roles in a variety of cellular processes during development and in adult tissues. PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DUSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic β cells. PTPMT1 exclusively localizes to the matrix face of the inner membrane of the mitochondrion. It is responsible for dephosphorylating mitochondrial proteins and therefore plays a significant role in the production of ATP and secretion of insulin. For its substrate, PTPMT1 displays a specific preference for the lipid signaling molecule, phosphatidylinositol 5-phosphate (PI(5)P).

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps PTPMT1 (B-12)

    sc-390947
    200 µg/ml
    $316.00

    PTPMT1 (B-12): m-IgGκ BP-HRP Kit

    sc-535666
    200 µg Ab; 40 µg BP
    $354.00

    PTPMT1 (B-12): m-IgG2a BP-HRP Kit

    sc-546229
    200 µg Ab; 10 µg BP
    $354.00

    Can PTPMT1 (B-12): sc-390947 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: Germaine
    Thank you for your question. Yes, PTPMT1 (B-12): sc-390947 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-02-27
    • y_2025, m_9, d_8, h_8CST
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    Rated 5 de 5 de par Produced beautiful immunoperoxidase cytoplasmicProduced beautiful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human lower stomach tissue. -SCBT QC
    Date de publication: 2015-03-22
    Rated 5 de 5 de par Satisfactory Western Blot data of PTPMT1Satisfactory Western Blot data of PTPMT1 expression in K-562, Ramos, HISM and MCF7 whole cell lysates. -SCBT QC
    Date de publication: 2013-02-19
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    Anticorps PTPMT1 (B-12) est évalué 5.0 de 5 de 2.
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