Date published: 2025-9-8

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Anticorps PINX1 (H-8): sc-376394

5.0(1)
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Fiches techniques
  • L'Anticorps PINX1 (H-8) est un monoclonal de souris IgG2b κ, cité dans 1 publications, fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 8-29 au niveau N-terminus de PINX1 d'origine human
  • recommandé pour la détection de PINX1 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • 2b BP-HRP">m-IgG2b BP-HRP est le réactif de détection secondaire préféré pour l'anticorps PINX1 (H-8) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps PINX1 (H-8)(voir les informations relatives à la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

PINX1 (PIN2/TRF1-interacting protein X1), also known as LPTL or LPTS (liver-related putative tumor suppressor), is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. PINX1 contains one G-patch domain and one telomeric inhibiting domain (TID) at its C-terminus. PINX1 interacts with the telomere protein TRF1 and the telomerase reverse transcriptase TERT. The TID domain of PINX1 specifically interacts with TERT and functions to inhibit its activity, thus participating in the regulation of telomerase activity. Overexpression of PINX1 leads to shortened telomeres, further supporting an inhibitory role of PINX1 on telomerase activity. The depletion of PINX1 significantly increases telomerase activity and may lead to tumorigenicity of cancer cells. This suggests that PINX1 acts as a tumor suppressor and can inhibit cell proliferation. In addition, PINX1 is involved in nucleolar RNA maturation.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps PINX1 (H-8)

sc-376394
200 µg/ml
$316.00

PINX1 (H-8): m-IgG2b BP-HRP Kit

sc-548596
200 µg Ab; 10 µg BP
$354.00

PINX1 (H-8) peptide neutralisant

sc-376394 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-376394 P appropriate for?

Posée par: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-03-01
  • y_2025, m_9, d_4, h_6CST
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Rated 5 de 5 de par Good Western blot data of PINX1 expression in nonGood Western blot data of PINX1 expression in non-transfected and human PINX1 transfected 293 whole cell lysates. -SCBT QC
Date de publication: 2013-07-12
  • y_2025, m_9, d_4, h_6
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Anticorps PINX1 (H-8) est évalué 5.0 de 5 de 1.
  • y_2025, m_9, d_4, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
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  • CLOUD, getAggregateRating, 120ms
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