L'Anticorps PI 4-kinase β (A-2) est un monoclonal de souris IgG1 κ, cité dans 1 publications, fourni en 200 µg/ml
raised against amino acids 1-300 mapping at the N-terminus of PI 4-kinase β of human origin
recommandé pour la détection de PI 4-kinase β d'origine human par WB, IP, IF, IHC(P) et ELISA
m-IgG1 BP-HRP est le réactif secondaire recommandé pour la détection de l'anticorps PI 4-kinase β (A-2) pour des applications de WB and IHC(P). Ce réactif est maintenant proposé en kit avec l'anticorps PI 4-kinase β (A-2) (voir Informations pour la commande ci-dessous).
Les Produits Chimiques ChemCruz™
PI 4-kinase Inhibiteurs pour l'analyse fonctionnelle des réponses cellulaires de PI 4-kinase
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The members of the phosphatidylinositol kinase (PIK) superfamily can be divided into three groups based on their substrate specificity. PIKs convert phosphatidylinositol (PI) into PI phosphate [PI(3)P], PI phosphate [PI(4)P], PI bisphosphate [PI(4,5)P2] and PI triphosphate [PI(3,4,5)P3]. The first group, the PI 3-kinases, is composed of highly related proteins designated p110α, p110β, p110γ and p110δ which convert PI into PI(3)P and PI(4,5)P2 into PI(3,4,5)P3. The second group, the PI 4-kinases, convert PI into PI(4)P. The third group, the PI(4)P5-kinases, convert PI(4)P into PI(4,5)P2. Phosphatidylinositides represent important regulatory molecules and are involved in a diverse array of signaling pathways. Phosphatidylinositol biphosphate acts as an activator of PKCs and as a substrate for PLC γ, which converts the molecule into the second messengers, Inositol-1,4,5 triphosphate and 1,2-diacylglycerol. PI(3,4,5)P3 has been shown to activate the PKC ζ isoform. PI 4-kinase β is a cytoplasmic protein inhibited by Wortmannin.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.