Anticorps PI 4-kinase β (A-2): sc-166822
- L'Anticorps PI 4-kinase β (A-2) est un monoclonal de souris IgG1 κ, cité dans 1 publications, fourni en 200 µg/ml
- soulevée à l'encontre des acides aminés 1-300 correspondant à N-terminus de PI 4-kinase β d'origine human.
- recommandé pour la détection de PI 4-kinase β d'origine human par WB, IP, IF, IHC(P) et ELISA
- 1 BP-HRP">m-IgG1 BP-HRP est le réactif de détection secondaire préféré pour l'anticorps PI 4-kinase β (A-2) pour les applications WB et IHC(P). Ce réactif est désormais proposé en association avec l'anticorps PI 4-kinase β (A-2)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The members of the phosphatidylinositol kinase (PIK) superfamily can be divided into three groups based on their substrate specificity. PIKs convert phosphatidylinositol (PI) into PI phosphate [PI(3)P], PI phosphate [PI(4)P], PI bisphosphate [PI(4,5)P2] and PI triphosphate [PI(3,4,5)P3]. The first group, the PI 3-kinases, is composed of highly related proteins designated p110α, p110β, p110γ and p110δ which convert PI into PI(3)P and PI(4,5)P2 into PI(3,4,5)P3. The second group, the PI 4-kinases, convert PI into PI(4)P. The third group, the PI(4)P5-kinases, convert PI(4)P into PI(4,5)P2. Phosphatidylinositides represent important regulatory molecules and are involved in a diverse array of signaling pathways. Phosphatidylinositol biphosphate acts as an activator of PKCs and as a substrate for PLC γ, which converts the molecule into the second messengers, Inositol-1,4,5 triphosphate and 1,2-diacylglycerol. PI(3,4,5)P3 has been shown to activate the PKC ζ isoform. PI 4-kinase β is a cytoplasmic protein inhibited by Wortmannin.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PI 4-kinase β (A-2) | sc-166822 | 200 µg/ml | $316.00 | |||
PI 4-kinase β (A-2): m-IgG1 BP-HRP Kit | sc-542672 | 200 µg Ab; 20 µg BP | $354.00 |