Date published: 2025-9-8

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Anticorps PELO (F-8): sc-393448

5.0(2)
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Fiches techniques
  • L'Anticorps PELO (F-8) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 1-231 situés au niveau N-terminus de PELO d'origine human
  • recommandé pour la détection de PELO d'origine mouse, rat et human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps PELO (F-8) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps PELO (F-8)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    PELO (pelota homolog), also known as CGI-17 or PRO1770, is a 385 amino acid nuclear and cytoplasmic protein that belongs to the eukaryotic release factor 1 family and the pelota subfamily. Evolutionary conserved, PELO may be involved in the regulation of cell proliferation and stem cell self-renewal, and is suggested to be required for normal chromosome segregation during cell division and genomic stability. PELO may possess ribonuclease activity and has the ability to recognize stalled ribosomes, thereby triggering endonucleolytic cleavage of mRNA, a mechanism that releases non-functional ribosomes and degrades damaged mRNAs. PELO is ubiquitously expressed and utilizes divalent metal cations as cofactors. PELO may be essential for spermatogenesis, cell cycle control and in meiotic cell division. PELO is encoded by a gene located on human chromosome 5q11.2.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps PELO (F-8)

    sc-393448
    200 µg/ml
    $316.00

    PELO (F-8): m-IgG Fc BP-HRP Kit

    sc-538220
    200 µg Ab; 10 µg BP
    $354.00

    PELO (F-8): m-IgGκ BP-HRP Kit

    sc-535788
    200 µg Ab; 40 µg BP
    $354.00

    PELO (F-8): m-IgG1 BP-HRP Kit

    sc-545585
    200 µg Ab; 20 µg BP
    $354.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with PELO (F-8): sc-393448 monoclonal antibody?

    Posée par: Cweed
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Répondue par: Technical Support
    Date de publication: 2017-02-27
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    Rated 5 de 5 de par Satisfactory Western Blot data of PELO expressionSatisfactory Western Blot data of PELO expression in HeLa and HEK293T whole cell lysates. -SCBT QC
    Date de publication: 2015-03-27
    Rated 5 de 5 de par Great Western Blot data of PELO expressionGreat Western Blot data of PELO expression in human stomach and mouse thymus tissue extracts. -SCBT QC
    Date de publication: 2013-10-11
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    Anticorps PELO (F-8) est évalué 5.0 de 5 de 2.
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