Anticorps Pdcd-2 (H-1): sc-393137
- L'Anticorps Pdcd-2 (H-1) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 259-344 situés au niveau C-terminus de Pdcd-2 d'origine human
- recommandé pour la détection de Pdcd-2 d'origine human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps Pdcd-2 (H-1) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps Pdcd-2 (H-1)(voir les informations de commande ci-dessous).
Pdcd-1 (Programmed Cell Death-1 protein) is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. Pdcd-1 contains an immunoreceptor tyrosine based inhibitory motif (ITIM) within the cytoplasmic domain, which is conserved between the mouse and human homologs. Expression of Pdcd-1 is detected in mouse thymus, and it is induced in stimulated B and T cell lines, where it may play a role in thenegative regulation of various immune responses. Receptors such as Pdcd-1 function by recruiting tyrosine phosphatases, including SHP-1 and SHIP, which are responsible for altering various B cell responses. Additionally, in activated lymphocytes, Pdcd-1 mediates the activation of the classical type of programmed cell death. A related protein, Pdcd-2 (also known as PD-2, PDL2, or B7DC), is highly expressed in placenta, heart, pancreas, lung, and liver, and lowly expressed in spleen, lymph nodes, and thymus.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Pdcd-2 (H-1) | sc-393137 | 200 µg/ml | $316.00 | |||
Pdcd-2 (H-1): m-IgG Fc BP-HRP Kit | sc-538150 | 200 µg Ab; 10 µg BP | $354.00 | |||
Pdcd-2 (H-1): m-IgGκ BP-HRP Kit | sc-535710 | 200 µg Ab; 40 µg BP | $354.00 | |||
Pdcd-2 (H-1): m-IgG2a BP-HRP Kit | sc-548218 | 200 µg Ab; 10 µg BP | $354.00 |