Date published: 2025-9-8

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Anticorps paxillin (C-10): sc-393149

5.0(1)
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Fiches techniques
  • L'Anticorps paxillin (C-10) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 59-89 près de N-terminus de paxillin d'origine human
  • recommandé pour la détection de paxillin α, β and γ isoforms d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Voir paxillin (B-2): sc-365379 pour d'autres anticorps conjugués paxillin, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps paxillin (C-10) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps paxillin (C-10)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Paxillin is a focal adhesion phosphoprotein that is localized to the cytoskeleton. Phosphorylation of paxillin has been shown to occur in response to PDGF treatment, v-src transformation or cross-linking of integrins. FAK (focal adhesion kinase) and PYK2 have been shown to phosphorylate paxillin. FAK phosphorylates paxillin specifically on Tyr 118 in vitro. However, FAK phosphorylation does not seem to be required for the recruitment of paxillin to cell adhesion sites. Paxillin may play a role in signal transduction, regulation of cell morphology and the recruitment of structural and signaling molecules to focal adhesions. It has been shown that the amount of paxillin is reduced in mitotic cells by proteolytic downregulation and that paxillin is alternatively phosphorylated on serine rather than on tyrosine and serine during mitosis.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps paxillin (C-10)

    sc-393149
    200 µg/ml
    $316.00

    paxillin (C-10): m-IgG Fc BP-HRP Kit

    sc-538153
    200 µg Ab; 10 µg BP
    $354.00

    paxillin (C-10): m-IgGκ BP-HRP Kit

    sc-535713
    200 µg Ab; 40 µg BP
    $354.00

    paxillin (C-10): m-IgG1 BP-HRP Kit

    sc-545550
    200 µg Ab; 20 µg BP
    $354.00

    paxillin (C-10) peptide neutralisant

    sc-393149 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-393149 P appropriate for?

    Posée par: AbPolly
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-02-24
    • y_2025, m_8, d_29, h_8CST
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    Rated 5 de 5 de par Produced positive Western blot data of paxillinProduced positive Western blot data of paxillin expression in CCD-1064Sk and HeLa whole cell lysates. -SCBT QC
    Date de publication: 2013-07-09
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    Anticorps paxillin (C-10) est évalué 5.0 de 5 de 1.
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