Date published: 2025-9-8

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Anticorps paxillin (A-5): sc-390738

5.0(1)
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Fiches techniques
  • L'Anticorps paxillin (A-5) est un monoclonal de souris IgG2b κ, cité dans 2 publications, fourni en 200 µg/ml
  • spécifique d'une correspondance épitopique entre les acides aminés 59-72 de paxillin de human d'origine
  • recommandé pour la détection de α, β and γ isoforms of paxillin d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Voir paxillin (B-2): sc-365379 pour d'autres anticorps conjugués paxillin, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • Le m-IgG Fc BP-HRP est le réactif de détection secondaire préféré pour l'anticorps paxillin (A-5) pour les applications WB. Ce réactif est désormais proposé en bundle avec l'anticorps paxillin (A-5)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Paxillin is a focal adhesion phosphoprotein that is localized to the cytoskeleton. Phosphorylation of paxillin has been shown to occur in response to PDGF treatment, v-src transformation or cross-linking of integrins. FAK (focal adhesion kinase) and PYK2 have been shown to phosphorylate paxillin. FAK phosphorylates paxillin specifically on Tyr 118 in vitro. However, FAK phosphorylation does not seem to be required for the recruitment of paxillin to cell adhesion sites. Paxillin may play a role in signal transduction, regulation of cell morphology and the recruitment of structural and signaling molecules to focal adhesions. It has been shown that the amount of paxillin is reduced in mitotic cells by proteolytic downregulation and that paxillin is alternatively phosphorylated on serine rather than on tyrosine and serine during mitosis.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps paxillin (A-5)

sc-390738
200 µg/ml
$316.00

paxillin (A-5): m-IgG Fc BP-HRP Kit

sc-540847
200 µg Ab; 10 µg BP
$354.00

paxillin (A-5) peptide neutralisant

sc-390738 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-390738 P appropriate for?

Posée par: jerojero
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-02-27
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Rated 5 de 5 de par Produced positive Western blot data of paxillinProduced positive Western blot data of paxillin expression in CCD-1064Sk and HeLa whole cell lysates. -SCBT QC
Date de publication: 2013-02-05
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Anticorps paxillin (A-5) est évalué 5.0 de 5 de 1.
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