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Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. PATZ1 (POZ (BTB) and AT hook containing zinc finger 1), also known as PATZ, RIAZ, ZBTB19, ZNF278 or ZSG, is a 687 amino acid protein that localizes to the nucleus and contains one A.T hook DNA-binding domain, one BTB (POZ) domain and seven C2H2-type zinc fingers. Expressed ubiquitously, PATZ1 functions as a transcriptional repressor and may be involved in the pathogenesis of small round cell sarcoma, as well as human colorectal cancer. Multiple isoforms of PATZ1 exist due to alternative splicing events.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PATZ1 (D-5) | sc-390577 | 200 µg/ml | $316.00 | |||
PATZ1 (D-5): m-IgG Fc BP-HRP Kit | sc-540819 | 200 µg Ab; 10 µg BP | $354.00 | |||
PATZ1 (D-5): m-IgG1 BP-HRP Kit | sc-542392 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps PATZ1 (D-5) X | sc-390577 X | 200 µg/0.1 ml | $316.00 |