pan nRNP Antibody (2Q2237) is an IgM mouse monoclonal pan nRNP antibody (also designated pan nRNP antibody) that detects the pan nRNP protein of human origin by IF, IHC(P) and FCM. pan nRNP Antibody (2Q2237) is available as the non-conjugated anti-pan nRNP antibody. Anti-nuclear antibodies remain prevalent in a large group of autoimmune disorders. The accumulation of anti-nuclear antibodies is characteristic of lupus erythematosus, as well as various other auto-immune diseases such as Sjögren's syndrome, autoimmune hepatitis, dermatomyositis, rheumatoid arthritis, and scleroderma. Ribonucleoproteins (RNP) represent a 20-80nm electron dense nuclear structure, with highest labeling densities found in nuclear ribonucleoprotein (nRNP) particles. One of the main components of the nucleolus, RNPs are comprised of ribonucleic acid (RNA) and protein together, representing an RNA binding motif in an RNA binding protein. Aromatic amino acid residues occupying this RNP motif, create stacking interactions with RNA. Lysine residues expressed exclusively in the helical portion of RNA binding proteins stabilizes relationships with nucleic acids. Pan nRNP antibodies provide detection for a range of RNP proteins.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps pan nRNP (2Q2237) | sc-71835 | 100 µg/ml | $316.00 |