ORP-3 (OSBP-related protein 3), also known as OSBPL3 (oxysterol binding protein-like 3) or OSBP3, is an 887 amino acid protein that contains one PH domain and is thought to be involved in Actin cytoskeletal control, as well as in cell polarity and cell adhesion.. Belonging to the OSBP family, ORP-3 exists as eight alternatively spliced isoforms, designated 1a-1d and 2a-2d, all of which are expressed in colon, lung, spleen, brain, thyroid, bone marrow and skeletal muscle, but are not present in liver and heart tissue. The gene encoding ORP-3 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ORP-3 (D-12) | sc-398326 | 200 µg/ml | $316.00 | |||
ORP-3 (D-12): m-IgG Fc BP-HRP Kit | sc-538419 | 200 µg Ab; 10 µg BP | $354.00 | |||
ORP-3 (D-12): m-IgGκ BP-HRP Kit | sc-536030 | 200 µg Ab; 40 µg BP | $354.00 | |||
ORP-3 (D-12): m-IgG2a BP-HRP Kit | sc-548294 | 200 µg Ab; 10 µg BP | $354.00 | |||
ORP-3 (D-12) peptide neutralisant | sc-398326 P | 100 µg/0.5 ml | $68.00 |