Anticorps Oas1a (C-8): sc-365357
- L'Anticorps Oas1a (C-8) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 308-367 situés au niveau C-terminus de Oas1a d'origine mouse
- recommandé pour la détection de Oas1a d'origine mouse et rat par WB, IP, IF et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-365357 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour Oas1a Antibody (C-8) for WB applications. Ces réactifs sont désormais proposés en lots avec Oas1a Antibody (C-8)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The 2'-, 5'- oligoadenylate synthetases (OASs) are interferon-induced proteins that play a putative role in mediating resistance to virus infection, control of cell growth, differentiation and apoptosis. OAS1, which functions as a homotetramer, is characterized by its capacity to catalyze the synthesis of 2'-, 5'- oligomers of adenosine (2-5As). OAS1 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, activating latent RNase L which, when activated, cleaves single-stranded RNAs. This RNase L activity leads to the inhibition of cellular protein synthesis and the impairment of viral replication. OAS1, a 400 amino acid containing protein, is also important in evaluating the interferon response in RNAi studies, and is implicated in diabetes mellitus susceptibility. Oas1a is one of the known rodent homologs of human OAS1, which are thought to mediate cell growth, differentiation and apoptosis, as well as host resistance to viral infection.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Oas1a (C-8) | sc-365357 | 200 µg/ml | $316.00 | |||
Oas1a (C-8): m-IgG Fc BP-HRP Kit | sc-540330 | 200 µg Ab; 10 µg BP | $354.00 | |||
Oas1a (C-8): m-IgG1 BP-HRP Kit | sc-542046 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps Oas1a (C-8) X | sc-365357 X | 200 µg/0.1 ml | $316.00 |