ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Nrl (neural retina leucine zipper) is a member of the Maf family of transcription factors, which characteristically contain a highly conserved basic leucine zipper (bZIP)-DNA binding motif. Both Nrl and c-Maf preferentially bind to T-MARE sites and are implicated in a wide variety of developmental and physiologic roles. The Maf-Nrl subfamily regulates the expression of cell type-specific genes in tissues of the hematopoietic system, cerebellum and developing hindbrain. Maf and Nrl proteins bind an extended AP-1-like sequence and can form heterodimers with Fos and Jun transcription factors. In retinal cells and photoreceptor cells, Nrl promotes the expression of rhodopsin through binding to the Nrl response element present in the rhodopsin promoter. Nrl is expressed throughout the developing central and peripheral nervous system during neuronal differentiation, and its expression is restricted to neocortex, brainstem and retinal neurons during adulthood.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Nrl (A-6) | sc-398046 | 200 µg/ml | $316.00 | |||
Nrl (A-6): m-IgG3 BP-HRP Kit | sc-550503 | 200 µg Ab; 40 µg BP | $354.00 | |||
Nrl (A-6) peptide neutralisant | sc-398046 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps Nrl (A-6) X | sc-398046 X | 200 µg/0.1 ml | $316.00 |