Anticorps Nrf2 (437C2a): sc-81342
- L'Anticorps Nrf2 (437C2a) est un monoclonal de souris IgG1 κ, cité dans 29 publications, fourni en 100 µg/ml
- soulevée contre une protéine recombinante correspondant à une région interne de Nrf2 d'origine human.
- recommandé pour la détection de Nrf2 d'origine human par WB et IP
- Voir Nrf2 (A-10): sc-365949 pour d'autres anticorps conjugués Nrf2, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Nrf2 (437C2a). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The NF-E2 DNA binding protein is composed of two subunits, p45 and MafK. It regulates expression of globin genes in developing erythroid cells through interaction with Maf recognition elements (Mares). A family of NF-E2- related proteins, which are collectively known as the Cap 'n' collar (CNC) family and include Nrf1 (also designated TCF11), Nrf2 and Nrf3, are bZIP transcription factors that heterodimerize with Maf proteins to bind Mare sequences. The Nrf proteins also bind the antioxidant response element (ARE) and are implicated in the regulation of detoxification enzymes and the oxidative stress response. They do so by heterodimerizing with Jun family members (c-Jun, Jun B and Jun D) to activate gene expression, specifically the detoxifying enzyme NQO1. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from its repressor protein, Keap1.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Nrf2 (437C2a) | sc-81342 | 100 µg/ml | $333.00 |