Anticorps NKp44 (3.43): sc-53598
- L'Anticorps NKp44 (3.43) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre NKp44 d'origine human
- recommandé pour la détection de NKp44 d'originie human par FCM
- disponible conjugué soit à la phycoérythrine soit à la FITC pour IF, IHC(P) et FCM
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps NKp44 (3.43). Ces réactifs sont désormais proposés en lots avec l'anticorps NKp44 (3.43)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
Natural killer (NK) cells direct cytotoxicity against tumor or virally infected cells. NK cell-mediated cytotoxicity is stimulated by several activating receptors associated with the signaling adapter DNAX activation 12/killer cell-activating receptor-associated protein (DAP12). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load. This implicates NKp44 as a therapeutic agent that may aid in the progress towards a vaccine for HIV-1 infection.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NKp44 (3.43) | sc-53598 | 200 µg/ml | $316.00 | |||
NKp44 (3.43): m-IgG Fc BP-HRP Kit | sc-536993 | 200 µg Ab; 10 µg BP | $354.00 | |||
NKp44 (3.43): m-IgGκ BP-HRP Kit | sc-534173 | 200 µg Ab; 40 µg BP | $354.00 | |||
NKp44 (3.43): m-IgG1 BP-HRP Kit | sc-544945 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps NKp44 (3.43) FITC | sc-53598 FITC | 200 µg/ml | $330.00 | |||
Anticorps NKp44 (3.43) PE | sc-53598 PE | 200 µg/ml | $343.00 |